Analysis of the CCR5 gene coding region diversity in five South American populations reveals two new non-synonymous alleles in Amerindians and high CCR5*D32 frequency in Euro-Brazilians

The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The effect of the CCR5*D32 allele in susceptibility to HIV infection and AIDS disease is well known. Other alleles than CCR5*D32 have not been analysed before, neither in Amerindians nor in the majority of the populatio...

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Detalhes bibliográficos
Main Authors: Boldt, Angelica B. W., Culpi, Lodércio, Tsuneto, Luiza T., Souza, Ilíada R., Kun, Jürgen F. J., Petzl-Erler, Maria Luiza
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Genética 2009
Assuntos:
Human and Medical Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032967/
https://ncbi.nlm.nih.gov/pubmed/21637640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572009005000011
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