Mapping of multiple HLA class II-restricted T-cell epitopes of the mycobacterial 70-kilodalton heat shock protein.

By combining a DNA subclone and synthetic-peptide approach, we mapped epitopes of the immunogenic mycobacterial 70-kDa heat shock protein (HSP70) recognized by human CD4+ T-cell clones and lines. In addition, we identified the respective HLA-DR molecules used in antigen presentation. The donor group...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Oftung, F, Geluk, A, Lundin, K E, Meloen, R H, Thole, J E, Mustafa, A S, Ottenhoff, T H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303282/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7525484/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.12.5411-5418.1994
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