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Diversity in Viral Anti-PKR Mechanisms: A Remarkable Case of Evolutionary Convergence

Most viruses express during infection products that prevent or neutralize the effect of the host dsRNA activated protein kinase (PKR). Translation of Sindbis virus (SINV) mRNA escapes to PKR activation and eIF2 phosphorylation in infected cells by a mechanism that requires a stem loop structure in v...

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Main Authors: Domingo-Gil, Elena, Toribio, René, Nájera, José Luis, Esteban, Mariano, Ventoso, Iván
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032782/
https://ncbi.nlm.nih.gov/pubmed/21311764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016711
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