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DNA Polymerase β as a Novel Target for Chemotherapeutic Intervention of Colorectal Cancer
Chemoprevention presents a major strategy for the medical management of colorectal cancer. Most drugs used for colorectal cancer therapy induce DNA-alkylation damage, which is primarily repaired by the base excision repair (BER) pathway. Thus, blockade of BER pathway is an attractive option to inhib...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032781/ https://ncbi.nlm.nih.gov/pubmed/21311763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016691 |
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