DNA Polymerase β as a Novel Target for Chemotherapeutic Intervention of Colorectal Cancer

Chemoprevention presents a major strategy for the medical management of colorectal cancer. Most drugs used for colorectal cancer therapy induce DNA-alkylation damage, which is primarily repaired by the base excision repair (BER) pathway. Thus, blockade of BER pathway is an attractive option to inhib...

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Bibliografiske detaljer
Main Authors: Jaiswal, Aruna S., Banerjee, Sanjeev, Aneja, Ritu, Sarkar, Fazlul H., Ostrov, David A., Narayan, Satya
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032781/
https://ncbi.nlm.nih.gov/pubmed/21311763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016691
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