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Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy

Evidence is mounting that proinflammatory and proapoptotic thioredoxin-interacting protein (TXNIP) has a causative role in the development of diabetes. However, there are no studies investigating the role of TXNIP in diabetic retinopathy (DR). Here, we show that, in diabetic rats, TXNIP expression a...

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Detalhes bibliográficos
Main Authors: Perrone, L, Devi, T S, Hosoya, K-I, Terasaki, T, Singh, L P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032527/
https://ncbi.nlm.nih.gov/pubmed/21364670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.42
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