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The transcriptional co-regulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles
The two p160 transcriptional co-regulator family members SRC-1 and TIF2 have important metabolic functions in white and brown adipose tissues, as well as in the liver. To analyze TIF2 cell-autonomous functions in skeletal muscles, we generated TIF2((i)skm-/-) mice, in which TIF2 was selectively abla...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032428/ https://ncbi.nlm.nih.gov/pubmed/21035760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.09.016 |
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