The transcriptional co-regulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles

The two p160 transcriptional co-regulator family members SRC-1 and TIF2 have important metabolic functions in white and brown adipose tissues, as well as in the liver. To analyze TIF2 cell-autonomous functions in skeletal muscles, we generated TIF2((i)skm-/-) mice, in which TIF2 was selectively abla...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Duteil, Delphine, Chambon, Céline, Ali, Faisal, Malivindi, Rocco, Zoll, Joffrey, Kato, Shigeaki, Geny, Bernard, Chambon, Pierre, Metzger, Daniel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032428/
https://ncbi.nlm.nih.gov/pubmed/21035760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.09.016
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