The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury

The activation of nuclear factor kappa B (NF-κB) p50/RelA is a key event in ischemic neuronal injury, as well as in brain ischemic tolerance. We tested whether epigenetic mechanisms affecting the acetylation state of RelA might discriminate between neuroprotective and neurotoxic activation of NF-κB...

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Autores principales: Lanzillotta, A, Sarnico, I, Ingrassia, R, Boroni, F, Branca, C, Benarese, M, Faraco, G, Blasi, F, Chiarugi, A, Spano, P, Pizzi, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032326/
https://ncbi.nlm.nih.gov/pubmed/21368872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.76
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