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CLIMP-63 is a gentamicin-binding protein that is involved in drug-induced cytotoxicity
Aminoglycoside-induced nephrotoxicity and ototoxicity is a major clinical problem. To understand how aminoglycosides, including gentamicin, induce cytotoxicity in the kidney proximal tubule and the inner ear, we identified gentamicin-binding proteins (GBPs) from mouse kidney cells by pulling down GB...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032319/ https://ncbi.nlm.nih.gov/pubmed/21368867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.80 |
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