p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

Medulloblastoma (MB) is an embryonic brain tumour that arises in the cerebellum. Using several MB cell lines, we have demonstrated that the chemotherapeutic drug etoposide induces a p53- and caspase-dependent cell death. We have observed an additional caspase-independent cell death mechanism involvi...

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Detalhes bibliográficos
Main Authors: Meley, D, Spiller, D G, White, M R H, McDowell, H, Pizer, B, Sée, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032310/
https://ncbi.nlm.nih.gov/pubmed/21364648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.16
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