p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

Medulloblastoma (MB) is an embryonic brain tumour that arises in the cerebellum. Using several MB cell lines, we have demonstrated that the chemotherapeutic drug etoposide induces a p53- and caspase-dependent cell death. We have observed an additional caspase-independent cell death mechanism involvi...

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Sonraí Bibleagrafaíochta
Main Authors: Meley, D, Spiller, D G, White, M R H, McDowell, H, Pizer, B, Sée, V
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2010
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032310/
https://ncbi.nlm.nih.gov/pubmed/21364648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.16
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