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The Coulter Principle for Analysis of Subvisible Particles in Protein Formulations

The Coulter principle can be used for analysis of subvisible particles in protein formulations. The approach has several advantages including: an orthogonal operating principle, high sensitivity, ability to detect very small particles, excellent reproducibility, and high-resolution size information....

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Bibliographic Details
Main Author: Rhyner, Matthew N.
Format: Artigo
Language:Inglês
Published: Springer US 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032098/
https://ncbi.nlm.nih.gov/pubmed/21161461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9245-6
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