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Powerful SNP-Set Analysis for Case-Control Genome-wide Association Studies

GWAS have emerged as popular tools for identifying genetic variants that are associated with disease risk. Standard analysis of a case-control GWAS involves assessing the association between each individual genotyped SNP and disease risk. However, this approach suffers from limited reproducibility a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Michael C., Kraft, Peter, Epstein, Michael P., Taylor, Deanne M., Chanock, Stephen J., Hunter, David J., Lin, Xihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032061/
https://ncbi.nlm.nih.gov/pubmed/20560208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.05.002
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