Llwytho...

Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6

To be effective, therapeutic compounds must typically enter target cells and, in some cases, must be concentrated or modified. Thus, uptake and activation mechanisms often form the basis of selectivity against infectious agents. Loss-of-function screens can be used to identify proteins involved in d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Baker, Nicola, Alsford, Sam, Horn, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier/North-Holland Biomedical Press 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032052/
https://ncbi.nlm.nih.gov/pubmed/21093499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.11.010
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