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Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans

The evolutionarily conserved heat shock transcription factor Hsf1 plays a central role in thermal adaptation in the major fungal pathogen of humans, Candida albicans. Hsf1 becomes hyperphosphorylated in response to heat shock and activates the transcription of genes with heat shock elements (HSEs) i...

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Autors principals: Nicholls, Susan, MacCallum, Donna M., Kaffarnik, Florian A.R., Selway, Laura, Peck, Scott C., Brown, Alistair J.P.
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032048/
https://ncbi.nlm.nih.gov/pubmed/20817114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2010.08.010
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