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Biocompatibility and Reduced Drug Absorption of Sol-Gel-Treated PDMS for Microfluidic Cell Culture Applications

Poly(dimethyl siloxane) (PDMS) -based microfluidic devices are now commonly used for a wide variety of biological experiments, including cell culture assays. However, the porous, hydrophobic polymer matrix of PDMS rapidly absorbs small hydrophobic molecules, including hormones and most small-molecul...

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Autores principales: Gomez-Sjoberg, Rafael, Leyrat, Anne A., Houseman, Benjamin T., Shokat, Kevan, Quake, Stephen R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032040/
https://ncbi.nlm.nih.gov/pubmed/20936785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac101870s
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