Acute and Long-Term Response of Dopamine Nigrostriatal Synapses to a Single Low Dose Episode of 3-Nitropropionic Acid-Mediated Chemical Hypoxia

The goal of the present investigation was to determine the persistence of striatal dopaminergic dysfunction after a mild chemically-induced hypoxic event in Fisher 344 rats. To this end, we gave a single injection of the mitochondrial complex II inhibitor 3-nitropropionic acid (3-NP; 16.5 mg/kg, i.p...

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Detalhes bibliográficos
Main Authors: Crawford, Cynthia A., Akopian, Garnik, Ring, Justin, Jakowec, Michael W., Petzinger, Giselle M., Andersen, Julie K., Vittozzi-Wong, Philip, Wang, Kristie, Farley, Cristal M., Charntikov, Sergios, Mitroi, Danut, Beal, M. Flint, Chow, Robert, Walsh, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032029/
https://ncbi.nlm.nih.gov/pubmed/20730800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20852
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