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Reducible DNA nanoparticles enhance in vitro gene transfer via an extracellular mechanism
We developed polylysine based DNA nanoparticles (DNA NPs) that contain disulfide linkage in the carrier and demonstrated that this reducible DNA NP enhances in vitro gene transfer via an extracellular mechanism. Polylysine was conjugated through an N-terminal cysteine to a polyethylene glycol chain...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031909/ https://ncbi.nlm.nih.gov/pubmed/20438780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.04.031 |
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