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HER2 directed small molecule antagonists

Inactivation of the HER2 tyrosine kinase holds significant promise as a cancer treatment hypothesis, making it a high value target for drug discovery. Screening and structure-based efforts have led to the development of several classes of ATP analog inhibitors of HER2 tyrosine kinase. These efforts...

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Hlavní autoři: Arkin, Michelle, Moasser, Mark M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031872/
https://ncbi.nlm.nih.gov/pubmed/19037833
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