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Enforced SOCS1 and SOCS3 expression attenuates Lck-mediated cellular transformation
Lck is a Src family protein tyrosine kinase with predominant T cell expression. Aberrant expression or activation of Lck kinase has been reported in both lymphoid and nonlymphoid malignancies. We showed previously that the signal transduction pathway involving Janus kinase (JAK) and signal transduce...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031791/ https://ncbi.nlm.nih.gov/pubmed/20372794 |
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