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Type I Interferons Protect from Toll-like Receptor 9-Associated Liver Injury and Regulate IL-1 Receptor Antagonist in Mice
BACKGROUND & AIMS: Liver inflammation and injury are mediated by the innate immune response, which is regulated by Toll-like receptors (TLR). Activation of TLR9 induces Type I interferons (IFNs) via the interferon regulatory factor (IRF)-7. We investigated the roles of Type I IFNs in TLR9-associ...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031737/ https://ncbi.nlm.nih.gov/pubmed/20727895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.08.020 |
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