Cisplatin induced Mitochondrial DNA Damage In Dorsal Root Ganglion Neurons

Cisplatin is a platinum-based chemotherapeutic agent that induces peripheral neuropathy in 30% of patients. Peripheral neuropathy is the dose limiting side effect, which has no preventative therapy. We have previously shown that cisplatin induces apoptosis in dorsal root ganglion (DRG) sensory neuro...

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Hlavní autoři: Podratz, Jewel L., Knight, Andrew M., Ta, Lauren E., Staff, Nathan P., Gass, Jennifer M., Genelin, Konstantin, Schlattau, Alexander, Lathroum, Liselle, Windebank, Anthony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031677/
https://ncbi.nlm.nih.gov/pubmed/21145397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.11.017
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