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Bortezomib alters microtubule polymerization and axonal transport in rat dorsal root ganglion neurons
Bortezomib is part of a newer class of chemotherapeutic agents whose mechanism of action is inhibition of the proteasome-ubiquitination system. Primarily used in multiple myeloma, bortezomib causes a sensory-predominant axonal peripheral neuropathy in approximately 30% of patients. There are no esta...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844018/ https://ncbi.nlm.nih.gov/pubmed/24035926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2013.09.001 |
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