Inaccurate DNA Synthesis in Cell Extracts of Yeast Producing Active Human DNA Polymerase Iota

Mammalian Pol ι has an unusual combination of properties: it is stimulated by Mn(2+) ions, can bypass some DNA lesions and misincorporates “G” opposite template “T” more frequently than incorporates the correct “A.” We recently proposed a method of detection of Pol ι activity in animal cell extracts...

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Bibliographic Details
Main Authors: Makarova, Alena V., Grabow, Corinn, Gening, Leonid V., Tarantul, Vyacheslav Z., Tahirov, Tahir H., Bessho, Tadayoshi, Pavlov, Youri I.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031609/
https://ncbi.nlm.nih.gov/pubmed/21304950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016612
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