The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes

BACKGROUND: The hydroxylated derivatives of cholesterol, such as the oxysterols, play important roles in lipid metabolism. In particular, 25-hydroxycholesterol (25HC) has been implicated in a variety of metabolic events including cholesterol homeostasis and atherosclerosis. 25HC is detectable in hum...

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Autors principals: Lappano, Rosamaria, Recchia, Anna Grazia, De Francesco, Ernestina Marianna, Angelone, Tommaso, Cerra, Maria Carmela, Picard, Didier, Maggiolini, Marcello
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031608/
https://ncbi.nlm.nih.gov/pubmed/21304949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016631
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