Propofol Directly Increases Tau Phosphorylation

In Alzheimer's disease (AD) and other tauopathies, the microtubule-associated protein tau can undergo aberrant hyperphosphorylation potentially leading to the development of neurofibrillary pathology. Anesthetics have been previously shown to induce tau hyperphosphorylation through a mechanism...

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Main Authors: Whittington, Robert A., Virág, László, Marcouiller, François, Papon, Marie-Amélie, Khoury, Noura B. El., Julien, Carl, Morin, Françoise, Emala, Charles W., Planel, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031597/
https://ncbi.nlm.nih.gov/pubmed/21304998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016648
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