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Activation of the Canonical Wnt/β-Catenin Pathway in ATF3-Induced Mammary Tumors
Female transgenic mice that constitutively overexpress the transcription factor ATF3 in the basal epithelium of the mammary gland develop mammary carcinomas with high frequency, but only if allowed to mate and raise pups early in life. This transgenic mouse model system reproduces some features of h...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031586/ https://ncbi.nlm.nih.gov/pubmed/21304988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016515 |
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