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Detoxication of sulfur half-mustards by nucleophilic scavengers: robust activity of thiopurines
Sulfur mustard (bis-(2-chloroethyl)sulfide) has been used in chemical warfare since World War I, and is well known as an acutely toxic vesicant. It has been implicated as a carcinogen after chronic low-level exposure, and is known to form inter-strand crosslinks in DNA. Sulfur and nitrogen mustards...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838965/ https://ncbi.nlm.nih.gov/pubmed/20050632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900190j |
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