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Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53

Statins inhibit the proximal steps of cholesterol biosynthesis, and are linked to health benefits in various conditions, including cancer and lung disease. We have previously investigated apoptotic pathways triggered by statins in airway mesenchymal cells, and identified reduced prenylation of small...

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Bibliografiset tiedot
Päätekijät: Ghavami, Saeid, Mutawe, Mark M., Sharma, Pawan, Yeganeh, Behzad, McNeill, Karol D., Klonisch, Thomas, Unruh, Helmut, Kashani, Hessam H., Schaafsma, Dedmer, Los, Marek, Halayko, Andrew J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031577/
https://ncbi.nlm.nih.gov/pubmed/21304979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016523
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