The Development and Characterization of a Human Mesothelioma In Vitro 3D Model to Investigate Immunotoxin Therapy

BACKGROUND: Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates. Tumor microenvironments, however, are difficult to study in vitro. Cells cultured as monolayers exhibit less resistance to therapy than those grown in vivo and an alternative research...

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Detalhes bibliográficos
Main Authors: Xiang, Xinran, Phung, Yen, Feng, Mingqian, Nagashima, Kunio, Zhang, Jingli, Broaddus, V. Courtney, Hassan, Raffit, FitzGerald, David, Ho, Mitchell
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031536/
https://ncbi.nlm.nih.gov/pubmed/21305058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014640
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