Differences in Reversion of Resistance Mutations to Wild-Type under Structured Treatment Interruption and Related Increase in Replication Capacity

BACKGROUND: The CPCRA 064 study examined the effect of structured treatment interruption (STI) of up to 4 months followed by salvage treatment in patients failing therapy with multi-drug resistant HIV. We examined the relationship between the reversion rate of major reverse transcriptase (RT) resist...

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Hlavní autoři: Paquet, Agnes C., Baxter, John, Weidler, Jodi, Lie, Yolanda, Lawrence, Jody, Kim, Rose, Bates, Michael, Coakley, Eoin, Chappey, Colombe
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031504/
https://ncbi.nlm.nih.gov/pubmed/21297946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014638
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