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Inhibition of cell adhesion by anti–P-selectin aptamer: a new potential therapeutic agent for sickle cell disease

Adhesive interactions between circulating sickle red blood cells (RBCs), leukocytes, and endothelial cells are major pathophysiologic events in sickle cell disease (SCD). To develop new therapeutics that efficiently inhibit adhesive interactions, we generated an anti–P-selectin aptamer and examined...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gutsaeva, Diana R., Parkerson, James B., Yerigenahally, Shobha D., Kurz, Jeffrey C., Schaub, Robert G., Ikuta, Tohru, Head, C. Alvin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031491/
https://ncbi.nlm.nih.gov/pubmed/20926770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-285718
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