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AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier properties

Adhesive forces at endothelial cell-cell borders maintain vascular integrity. cAMP enhances barrier properties and controls cellular processes through protein kinase A bound to A-kinase anchoring proteins (AKAPs). It also activates exchange protein directly activated by cAMP (Epac1), an exchange fac...

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Detalhes bibliográficos
Main Authors: Sehrawat, Seema, Ernandez, Thomas, Cullere, Xavier, Takahashi, Mikiko, Ono, Yoshitaka, Komarova, Yulia, Mayadas, Tanya N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031489/
https://ncbi.nlm.nih.gov/pubmed/20952690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-268870
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