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An RNA-zipcode-independent mechanism that localizes Dia1 mRNA to the perinuclear ER through interactions between Dia1 nascent peptide and Rho–GTP

Signal-peptide-mediated ER localization of mRNAs encoding for membrane and secreted proteins, and RNA-zipcode-mediated intracellular targeting of mRNAs encoding for cytosolic proteins are two well-known mechanisms for mRNA localization. Here, we report a previously unidentified mechanism by which mR...

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Autors principals: Liao, Guoning, Ma, Xinghong, Liu, Gang
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031370/
https://ncbi.nlm.nih.gov/pubmed/21266463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.072421
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