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Fine Mapping of Calcineurin (PPP3CA) Gene Reveals Novel Alternative Splicing Patterns, Association of 5′UTR Trinucleotide Repeat With Addiction Vulnerability, and Differential Isoform Expression in Alzheimer's Disease

Fine mapping of calcineurin (PPP3CA) gene identified single nucleotide polymorphisms (SNPs) and simple sequence repeat polymorphisms that are associated with addiction vulnerability. A trinucleotide repeat marker, located in the 5′ untranslated region (5′UTR) of the PPP3CA mRNA, exhibited significan...

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Detalhes bibliográficos
Main Authors: CHIOCCO, MATTHEW J., ZHU, XUGUANG, WALTHER, DONNA, PLETNIKOVA, OLGA, TRONCOSO, JUAN C., UHL, GEORGE R., LIU, QING-RONG
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031160/
https://ncbi.nlm.nih.gov/pubmed/20590401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10826084.2010.482449
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