Fine Mapping of Calcineurin (PPP3CA) Gene Reveals Novel Alternative Splicing Patterns, Association of 5′UTR Trinucleotide Repeat With Addiction Vulnerability, and Differential Isoform Expression in Alzheimer's Disease

Fine mapping of calcineurin (PPP3CA) gene identified single nucleotide polymorphisms (SNPs) and simple sequence repeat polymorphisms that are associated with addiction vulnerability. A trinucleotide repeat marker, located in the 5′ untranslated region (5′UTR) of the PPP3CA mRNA, exhibited significan...

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Bibliografski detalji
Glavni autori: CHIOCCO, MATTHEW J., ZHU, XUGUANG, WALTHER, DONNA, PLETNIKOVA, OLGA, TRONCOSO, JUAN C., UHL, GEORGE R., LIU, QING-RONG
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031160/
https://ncbi.nlm.nih.gov/pubmed/20590401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10826084.2010.482449
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