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Loss of DNAM-1 contributes to CD8(+) T cell exhaustion in chronic HIV-1 infection
The hallmark of chronic viral infections is a progressive exhaustion of antigen specific CD8(+) T cells that leads to persisting viral replication. It is generally believed that exhaustion is a consequence of the accumulation of multiple inhibitory receptors on CD8(+) T cells that makes them dysfunc...
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031090/ https://ncbi.nlm.nih.gov/pubmed/20201043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940234 |
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