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Solution NMR Structure of apo-calmodulin in complex with the IQ motif of Human Cardiac Sodium Channel Na(V)1.5

The function of the human voltage-gated sodium channel Na(V)1.5 is regulated in part by intracellular calcium signals. The ubiquitous calcium sensor protein calmodulin (CaM) is an important part of the complex calcium-sensing apparatus in Na(V)1.5. CaM interacts with an IQ motif in the large intrace...

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Detalhes bibliográficos
Main Authors: Chagot, Benjamin, Chazin, Walter J
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030672/
https://ncbi.nlm.nih.gov/pubmed/21167176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.046
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