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XPB Mediated Retroviral cDNA Degradation Coincides with Entry to the Nucleus
Retroviruses must integrate their cDNA to a host chromosome, but a significant fraction of retroviral cDNA is degraded before integration. XPB and XPD are part of the TFIIH complex which mediates basal transcription and DNA nucleotide excision repair. Retroviral infection increases when XPB or XPD a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030651/ https://ncbi.nlm.nih.gov/pubmed/21167544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.11.016 |
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