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The DNA repair genes XPB and XPD defend cells from retroviral infection

Reverse transcription of retroviral RNA genomes produce a double-stranded linear cDNA molecule. A host degradation system prevents a majority of the cDNA molecules from completing the obligatory genomic integration necessary for pathogenesis. We demonstrate that the human TFIIH complex proteins XPB...

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Autors principals: Yoder, Kristine, Sarasin, Alain, Kraemer, Kenneth, McIlhatton, Michael, Bushman, Frederic, Fishel, Richard
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450221/
https://ncbi.nlm.nih.gov/pubmed/16537383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509828103
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