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The E2F-1 associated retinoblastoma-susceptibility gene product is modified by O-GlcNAc

The retinoblastoma-susceptibility gene product (pRB) is a classical tumor suppressor. pRB regulates a number of cellular processes including proliferation, differentiation, and apoptosis. One of the essential mechanisms by which pRB, and the related p107 and p130 family members, act is through its i...

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Autori principali: Wells, Lance, Slawson, Chad, Hart, Gerald W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030635/
https://ncbi.nlm.nih.gov/pubmed/20680651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-010-0709-x
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