HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

Voltage-gated proton currents regulate generation of reactive oxygen species (ROS) in phagocytic cells. In B cells, stimulation of the B cell antigen receptor (BCR) results in the production of ROS that participate in B cell activation, but the involvement of proton channels is unknown. We report he...

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Detalhes bibliográficos
Main Authors: Capasso, Melania, Bhamrah, Mandeep K, Henley, Tom, Boyd, Robert S, Langlais, Claudia, Cain, Kelvin, Dinsdale, David, Pulford, Karen, Kan, Mahmood, Musset, Boris, Cherny, Vladimir V, Morgan, Deri, Gascoyne, Randy D, Vigorito, Elena, DeCoursey, Thomas E, MacLennan, Ian C M, Dyer, Martin J S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030552/
https://ncbi.nlm.nih.gov/pubmed/20139987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1843
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