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Identification of Thr(29) as a Critical Phosphorylation Site That Activates the Human Proton Channel Hvcn1 in Leukocytes
Voltage-gated proton channels and NADPH oxidase function cooperatively in phagocytes during the respiratory burst, when reactive oxygen species are produced to kill microbial invaders. Agents that activate NADPH oxidase also enhance proton channel gating profoundly, facilitating its roles in charge...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820736/ https://ncbi.nlm.nih.gov/pubmed/20037153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.082727 |
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