Identification of Thr(29) as a Critical Phosphorylation Site That Activates the Human Proton Channel Hvcn1 in Leukocytes

Voltage-gated proton channels and NADPH oxidase function cooperatively in phagocytes during the respiratory burst, when reactive oxygen species are produced to kill microbial invaders. Agents that activate NADPH oxidase also enhance proton channel gating profoundly, facilitating its roles in charge...

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Autores principales: Musset, Boris, Capasso, Melania, Cherny, Vladimir V., Morgan, Deri, Bhamrah, Mandeep, Dyer, Martin J. S., DeCoursey, Thomas E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820736/
https://ncbi.nlm.nih.gov/pubmed/20037153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.082727
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