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Molecular Characterization of a Novel Geranylgeranyl Pyrophosphate Synthase from Plasmodium Parasites

We present here a study of a eukaryotic trans-prenylsynthase from the malaria pathogen Plasmodium vivax. Based on the results of biochemical assays and contrary to previous indications, this enzyme catalyzes the production of geranylgeranyl pyrophosphate (GGPP) rather than farnesyl pyrophosphate (FP...

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Detalhes bibliográficos
Main Authors: Artz, Jennifer D., Wernimont, Amy K., Dunford, James E., Schapira, Matthieu, Dong, Aiping, Zhao, Yong, Lew, Jocelyne, Russell, R. Graham G., Ebetino, F. Hal, Oppermann, Udo, Hui, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030337/
https://ncbi.nlm.nih.gov/pubmed/21084289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027235
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