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The roles of TTP and BRF proteins in regulated mRNA decay

AU-rich element (ARE) motifs are cis-acting elements present in the 3′UTR of mRNA transcripts that encode many inflammation- and cancer-associated genes. The TIS11 family of RNA-binding proteins, composed of TTP, BRF-1, and BRF-2 play a critical role in regulating the expression of ARE-containing mR...

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Detalhes bibliográficos
Main Authors: Sanduja, Sandhya, Blanco, Fernando F., Dixon, Dan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030256/
https://ncbi.nlm.nih.gov/pubmed/21278925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.28
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