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Genome-wide association study of CSF biomarkers Aβ(1-42), t-tau, and p-tau(181p) in the ADNI cohort

OBJECTIVES: CSF levels of Aβ(1-42), t-tau, and p-tau(181p) are potential early diagnostic markers for probable Alzheimer disease (AD). The influence of genetic variation on these markers has been investigated for candidate genes but not on a genome-wide basis. We report a genome-wide association stu...

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Autors principals: Kim, S., Swaminathan, S., Shen, L., Risacher, S.L., Nho, K., Foroud, T., Shaw, L.M., Trojanowski, J.Q., Potkin, S.G., Huentelman, M.J., Craig, D.W., DeChairo, B.M., Aisen, P.S., Petersen, R.C., Weiner, M.W., Saykin, A.J.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030225/
https://ncbi.nlm.nih.gov/pubmed/21123754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318204a397
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