Reduced CSF p-Tau(181) to Tau ratio is a biomarker for FTLD-TDP

OBJECTIVES: To validate the ability of candidate CSF biomarkers to distinguish between the 2 main forms of frontotemporal lobar degeneration (FTLD), FTLD with TAR DNA-binding protein 43 (TDP-43) inclusions (FTLD-TDP) and FTLD with Tau inclusions (FTLD-Tau). METHODS: Antemortem CSF samples were colle...

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Main Authors: Hu, William T., Watts, Kelly, Grossman, Murray, Glass, Jonathan, Lah, James J., Hales, Chadwick, Shelnutt, Matthew, Van Deerlin, Vivianna, Trojanowski, John Q., Levey, Allan I.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843382/
https://ncbi.nlm.nih.gov/pubmed/24174584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000436625.63650.27
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