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Dilutional Control of Prothrombin Activation at Physiologically Relevant Shear Rates

The generation of proteolyzed prothrombin species by preassembled prothrombinase in phospholipid-coated glass capillaries was studied at physiologic shear rates (100–1000 s(−1)). The concentration of active thrombin species (α-thrombin and meizothrombin) reaches a steady state, which varies inversel...

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Detalhes bibliográficos
Main Authors: Haynes, Laura M., Dubief, Yves C., Orfeo, Thomas, Mann, Kenneth G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030158/
https://ncbi.nlm.nih.gov/pubmed/21281592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.12.3720
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