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OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users

Substrates for the Organic Cation Transporter 1, encoded by the SLC22A1 gene, are metformin, amantadine, pramipexole, and, possibly, levodopa. Recently, we identified that the rs622342 A > C polymorphism is associated with the HbA1c lowering effect in metformin users. In the Rotterdam Study, we a...

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Autors principals: Becker, Matthijs L., Visser, Loes E., van Schaik, Ron H. N., Hofman, Albert, Uitterlinden, André G., Stricker, Bruno H. Ch.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029819/
https://ncbi.nlm.nih.gov/pubmed/20680652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-010-0254-5
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